THRB
thyroid hormone receptor, beta
Synonyms:
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Species:
Human THRB (7068), Mouse Thrb (21834), Rat Thrb (24831), Domestic Rabbit THRB (100303763), chicken THRB (396431), cow THRB (788329), domestic cat THRB (101084821), Horse THRB (100051615), dog THRB (403599), naked mole-rat Thrb (101719651) ...More
UniProtKB ID:
Gene ID:
- Human(7068) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
- Mouse(21834) thyroid hormone receptor beta
- Rat(24831) thyroid hormone receptor beta
- Domestic Rabbit(100303763) thyroid hormone receptor, beta
- chicken(396431) thyroid hormone receptor, beta
- cow(788329) thyroid hormone receptor, beta
- domestic cat(101084821) thyroid hormone receptor, beta
- Horse(100051615) thyroid hormone receptor, beta
- dog(403599) thyroid hormone receptor, beta
- naked mole-rat(101719651) thyroid hormone receptor, beta
- domestic guinea pig(100721125) thyroid hormone receptor, beta
- Zebrafish(30607) thyroid hormone receptor beta
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