TGFBR1
transforming growth factor, beta receptor 1
Synonyms:
AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, MSSE, SKR4, TGFR-1
Species:
Human TGFBR1 (7046), Mouse Tgfbr1 (21812), Rat Tgfbr1 (29591), chicken TGFBR1 (374094), dog TGFBR1 (481628), sheep TGFBR1 (554326), cow TGFBR1 (282382), domestic cat TGFBR1 (101094057), naked mole-rat Tgfbr1 (101718090), domestic guinea pig Tgfbr1 (100715237)
UniProtKB ID:
Gene ID:
- Human(7046) Summary: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(21812) transforming growth factor, beta receptor I
- Rat(29591) transforming growth factor, beta receptor 1
- chicken(374094) transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)
- dog(481628) transforming growth factor, beta receptor 1
- sheep(554326) transforming growth factor, beta receptor 1
- cow(282382) transforming growth factor, beta receptor 1
- domestic cat(101094057) transforming growth factor, beta receptor 1
- naked mole-rat(101718090) transforming growth factor, beta receptor 1
- domestic guinea pig(100715237) transforming growth factor, beta receptor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.