Skip to Content
Merck

TCF4

transcription factor 4

Synonyms:
E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, bHLHb19
Species:
UniProtKB ID:
Gene ID:
  • Human(6925) Summary: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Aug 2011]
  • Mouse(21413) transcription factor 4
  • Rat(84382) transcription factor 4
  • domestic guinea pig(100732402) transcription factor 4
  • naked mole-rat(101707519) transcription factor 4
  • cow(534935) transcription factor 4
  • sheep(101120538) transcription factor 4
  • dog(403949) transcription factor 4
  • Zebrafish(100526651) transcription factor 4
  • domestic cat(101097354) transcription factor 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.