TBXAS1
thromboxane A synthase 1 (platelet)
Synonyms:
BDPLT14, CYP5, CYP5A1, GHOSAL, THAS, TS, TXAS, TXS
Species:
Human TBXAS1 (6916), Mouse Tbxas1 (21391), Rat Tbxas1 (24886), Zebrafish tbxas1 (792041), cow TBXAS1 (509326), domestic cat TBXAS1 (101091097), Horse TBXAS1 (100066198), dog TBXAS1 (482771), domestic guinea pig Tbxas1 (100719442), Domestic Rabbit TBXAS1 (100339354) ...More
UniProtKB ID:
Gene ID:
- Human(6916) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(21391) thromboxane A synthase 1, platelet
- Rat(24886) thromboxane A synthase 1, platelet
- Zebrafish(792041) thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A)
- cow(509326) thromboxane A synthase 1 (platelet)
- domestic cat(101091097) thromboxane A synthase 1 (platelet)
- Horse(100066198) thromboxane A synthase 1 (platelet)
- dog(482771) thromboxane A synthase 1 (platelet)
- domestic guinea pig(100719442) thromboxane A synthase 1 (platelet)
- Domestic Rabbit(100339354) thromboxane A synthase 1 (platelet)
- sheep(101111361) thromboxane A synthase 1 (platelet)
- chicken(418101) thromboxane A synthase 1 (platelet)
- naked mole-rat(101697368) thromboxane A synthase 1 (platelet)
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