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Merck

TAF6L

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

Synonyms:
PAF65A
Species:
Human TAF6L (10629), Mouse Taf6l (225895), Rat Taf6l (309194), Zebrafish taf6l (557363), cow TAF6L (531109), domestic cat TAF6L (101088188), dog TAF6L (476051), sheep TAF6L (101112524), naked mole-rat Taf6l (101698270), domestic guinea pig Taf6l (100733115)
UniProtKB ID:
Q9Y6J9, B2RAT0, Q96HA6
Gene ID:
  • Human(10629) Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. [provided by RefSeq, Jul 2008]
  • Mouse(225895) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
  • Rat(309194) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
  • Zebrafish(557363) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
  • cow(531109) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • domestic cat(101088188) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • dog(476051) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • sheep(101112524) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • naked mole-rat(101698270) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • domestic guinea pig(100733115) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

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