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Merck

SUMO2

small ubiquitin-like modifier 2

Synonyms:
HSMT3, SMT3B, SMT3H2, SUMO3, Smt3A
Species:
UniProtKB ID:
Gene ID:
  • Human(6613) Summary: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(170930) SMT3 suppressor of mif two 3 homolog 2 (yeast)
  • Rat(690244) small ubiquitin-like modifier 2
  • chicken(770125) SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
  • Thale Cress(835609) small ubiquitin-related modifier 2
  • domestic guinea pig(100727754) small ubiquitin-like modifier 2
  • sheep(101121694) SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
  • cow(286807) SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
  • domestic cat(101094221) SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
  • dog(474963) SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)

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