Skip to Content
Merck

STK3

serine/threonine kinase 3

Synonyms:
KRS1, MST2
Species:
UniProtKB ID:
Gene ID:
  • Human(6788) Summary: This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(56274) serine/threonine kinase 3
  • Rat(65189) serine/threonine kinase 3
  • Horse(100060508) serine/threonine kinase 3
  • Zebrafish(324125) serine/threonine kinase 3 (STE20 homolog, yeast)
  • domestic guinea pig(100729700) serine/threonine kinase 3
  • sheep(101106085) serine/threonine kinase 3
  • naked mole-rat(101715099) serine/threonine kinase 3
  • chicken(425375) serine/threonine kinase 3
  • dog(475045) serine/threonine kinase 3
  • cow(533815) serine/threonine kinase 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.