STAT2
signal transducer and activator of transcription 2, 113kDa
Synonyms:
ISGF-3, P113, STAT113
Species:
Human STAT2 (6773), Mouse Stat2 (20847), Rat Stat2 (288774), dog STAT2 (481111), sheep STAT2 (101108211), cow STAT2 (511023), naked mole-rat Stat2 (101707295), domestic cat STAT2 (101099224), domestic guinea pig Stat2 (100719719), Zebrafish stat2 (565200)
UniProtKB ID:
Gene ID:
- Human(6773) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
- Mouse(20847) signal transducer and activator of transcription 2
- Rat(288774) signal transducer and activator of transcription 2
- dog(481111) signal transducer and activator of transcription 2, 113kDa
- sheep(101108211) signal transducer and activator of transcription 2, 113kDa
- cow(511023) signal transducer and activator of transcription 2, 113kDa
- naked mole-rat(101707295) signal transducer and activator of transcription 2, 113kDa
- domestic cat(101099224) signal transducer and activator of transcription 2, 113kDa
- domestic guinea pig(100719719) signal transducer and activator of transcription 2, 113kDa
- Zebrafish(565200) signal transducer and activator of transcription 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-STAT2 (Tyr689) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
inhibition assay
western blot
inhibition assay
western blot
Anti-STAT2 Antibody, Upstate®, from rabbit,
Species Reactivity
mouse
Application
electrophoretic mobility shift assay
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Anti-STAT2 Antibody, CT, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
electrophoretic mobility shift assay
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot