SRGN
serglycin
Synonyms:
PPG, PRG, PRG1
Species:
Human SRGN (5552), Mouse Srgn (19073), Rat Srgn (56782), domestic cat SRGN (101093397), domestic guinea pig Srgn (100720359), naked mole-rat Srgn (101706972), chicken SRGN (423695), Zebrafish srgn (570867), cow SRGN (509501), dog SRGN (609421)
UniProtKB ID:
Gene ID:
- Human(5552) Summary: This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(19073) serglycin
- Rat(56782) serglycin
- domestic cat(101093397) serglycin
- domestic guinea pig(100720359) serglycin
- naked mole-rat(101706972) serglycin
- chicken(423695) serglycin
- Zebrafish(570867) serglycin
- cow(509501) serglycin
- dog(609421) serglycin
- sheep(101107327) serglycin
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