SPAST
spastin
Synonyms:
ADPSP, FSP2, SPG4
Species:
Human SPAST (6683), Mouse Spast (50850), Rat Spast (362700), sheep SPAST (101104819), cow SPAST (521442), domestic cat SPAST (101088156), dog SPAST (608582), Zebrafish spast (405851), Domestic Rabbit SPAST (100345919), domestic guinea pig Spast (100732493) ...More
UniProtKB ID:
Gene ID:
- Human(6683) Summary: This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq, Jul 2008]
- Mouse(50850) spastin
- Rat(362700) spastin
- sheep(101104819) spastin
- cow(521442) spastin
- domestic cat(101088156) spastin
- dog(608582) spastin
- Zebrafish(405851) spastin
- Domestic Rabbit(100345919) spastin
- domestic guinea pig(100732493) spastin
- chicken(421481) spastin
- naked mole-rat(101710272) spastin
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.