SP100
SP100 nuclear antigen
Synonyms:
lysp100b
Species:
Human SP100 (6672), Mouse Sp100 (20684), Rat Sp100 (363269), cow SP100 (100140338), naked mole-rat Sp100 (101725529), domestic guinea pig Sp100 (100727417), sheep SP100 (101120993), Horse SP100 (100063667), domestic cat SP100 (101093955), dog SP100 (477402)
UniProtKB ID:
Gene ID:
- Human(6672) Summary: This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]
- Mouse(20684) nuclear antigen Sp100
- Rat(363269) SP100 nuclear antigen
- cow(100140338) SP100 nuclear antigen
- naked mole-rat(101725529) SP100 nuclear antigen
- domestic guinea pig(100727417) SP100 nuclear antigen
- sheep(101120993) SP100 nuclear antigen
- Horse(100063667) SP100 nuclear antigen
- domestic cat(101093955) SP100 nuclear antigen
- dog(477402) SP100 nuclear antigen
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