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Merck

SMARCE1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

Synonyms:
BAF57
Species:
UniProtKB ID:
Gene ID:
  • Human(6605) Summary: The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008]
  • Mouse(57376) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • Rat(303518) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • cow(540910) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • naked mole-rat(101701675) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • domestic guinea pig(100731273) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • sheep(101109721) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • Horse(100054136) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • dog(608250) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • Zebrafish(322248) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • chicken(420047) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • domestic cat(101084584) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

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