SKIL
SKI-like oncogene
Synonyms:
SNO, SnoA, SnoI, SnoN
Species:
Human SKIL (6498), Mouse Skil (20482), Rat Skil (114208), naked mole-rat Skil (101725063), Horse SKIL (100057606), cow SKIL (527910), domestic cat SKIL (101096594), Domestic Rabbit SKIL (100351337), dog SKIL (488159), sheep SKIL (101117895) ...More
UniProtKB ID:
Gene ID:
- Human(6498) Summary: The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Mouse(20482) SKI-like
- Rat(114208) SKI-like oncogene
- naked mole-rat(101725063) SKI-like oncogene
- Horse(100057606) SKI-like oncogene
- cow(527910) SKI-like oncogene
- domestic cat(101096594) SKI-like oncogene
- Domestic Rabbit(100351337) SKI-like oncogene
- dog(488159) SKI-like oncogene
- sheep(101117895) SKI-like oncogene
- domestic guinea pig(100732257) SKI-like oncogene
- chicken(396087) SKI-like oncogene
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