SGMS2
sphingomyelin synthase 2
Synonyms:
SMS2
Species:
Human SGMS2 (166929), Mouse Sgms2 (74442), Rat Sgms2 (310849), domestic guinea pig Sgms2 (100715504), naked mole-rat Sgms2 (101712715), sheep SGMS2 (101123121), domestic cat SGMS2 (101088574), Horse SGMS2 (100072971), cow SGMS2 (520954), dog SGMS2 (478505) ...More
UniProtKB ID:
Gene ID:
- Human(166929) Summary: Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined.[provided by RefSeq, Oct 2008]
- Mouse(74442) sphingomyelin synthase 2
- Rat(310849) sphingomyelin synthase 2
- domestic guinea pig(100715504) sphingomyelin synthase 2
- naked mole-rat(101712715) sphingomyelin synthase 2
- sheep(101123121) sphingomyelin synthase 2
- domestic cat(101088574) sphingomyelin synthase 2
- Horse(100072971) sphingomyelin synthase 2
- cow(520954) sphingomyelin synthase 2
- dog(478505) sphingomyelin synthase 2
- Zebrafish(556193) sphingomyelin synthase 2
- chicken(422529) sphingomyelin synthase 2
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