SFRP1
secreted frizzled-related protein 1
Synonyms:
FRP, FRP-1, FRP1, FrzA, SARP2
Species:
Human SFRP1 (6422), Mouse Sfrp1 (20377), Rat Sfrp1 (84402), cow SFRP1 (282068), sheep SFRP1 (101121066), dog SFRP1 (482844), domestic cat SFRP1 (101083585), chicken SFRP1 (395237), naked mole-rat Sfrp1 (101716300), domestic guinea pig Sfrp1 (100727192)
UniProtKB ID:
Gene ID:
- Human(6422) Summary: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]
- Mouse(20377) secreted frizzled-related protein 1
- Rat(84402) secreted frizzled-related protein 1
- cow(282068) secreted frizzled-related protein 1
- sheep(101121066) secreted frizzled-related protein 1
- dog(482844) secreted frizzled-related protein 1
- domestic cat(101083585) secreted frizzled-related protein 1
- chicken(395237) secreted frizzled-related protein 1
- naked mole-rat(101716300) secreted frizzled-related protein 1
- domestic guinea pig(100727192) secreted frizzled-related protein 1
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