SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Synonyms:
CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
Species:
Human SDHB (6390), Mouse Sdhb (67680), Rat Sdhb (298596), Horse SDHB (100050091), Zebrafish sdhb (562149), chicken SDHB (100859720), fruit fly SdhB (35590), domestic guinea pig Sdhb (100728812), naked mole-rat Sdhb (101720891), cow SDHB (286840) ...More
UniProtKB ID:
Gene ID:
- Human(6390) Summary: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]
- Mouse(67680) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- Rat(298596) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- Horse(100050091) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- Zebrafish(562149) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- chicken(100859720) succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial-like
- fruit fly(35590) Succinate dehydrogenase B
- domestic guinea pig(100728812) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- naked mole-rat(101720891) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- cow(286840) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- sheep(101108729) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- Domestic Rabbit(100328585) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- dog(478217) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- domestic cat(751617) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
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