SCN5A
sodium channel, voltage-gated, type V, alpha subunit
Synonyms:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Species:
Human SCN5A (6331), Mouse Scn5a (20271), Rat Scn5a (25665), Domestic Rabbit SCN5A (100009516), domestic guinea pig Scn5a (100723340), naked mole-rat Scn5a (101710111), domestic cat SCN5A (101100994), Horse SCN5A (100034027), cow SCN5A (282061), sheep SCN5A (101111582) ...More
UniProtKB ID:
Gene ID:
- Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(20271) sodium channel, voltage-gated, type V, alpha
- Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
- Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
- domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
- naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
- domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
- Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
- cow(282061) sodium channel, voltage-gated, type V, alpha subunit
- sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
- chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
- dog(403497) sodium channel, voltage-gated, type V, alpha subunit
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Small Molecule - Blocker
Product Number
Description
Species
Flecainide for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human