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RUNX1

runt-related transcription factor 1

Synonyms:
AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
Species:
UniProtKB ID:
Gene ID:
  • Human(861) Summary: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12394) runt related transcription factor 1
  • Rat(50662) runt-related transcription factor 1
  • chicken(396152) runt-related transcription factor 1
  • Zebrafish(58126) runt-related transcription factor 1
  • sheep(101108280) runt-related transcription factor 1
  • Domestic Rabbit(100358993) runt-related transcription factor 1
  • domestic guinea pig(100724149) runt-related transcription factor 1
  • domestic cat(101084898) runt-related transcription factor 1
  • cow(529631) runt-related transcription factor 1
  • dog(487746) runt-related transcription factor 1
  • naked mole-rat(101705852) runt-related transcription factor 1

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