RNF139
ring finger protein 139
Synonyms:
HRCA1, RCA1, TRC8
Species:
Human RNF139 (11236), Mouse Rnf139 (75841), Rat Rnf139 (315000), chicken RNF139 (420338), sheep RNF139 (101102651), naked mole-rat Rnf139 (101714326), domestic cat RNF139 (101090488), Zebrafish rnf139 (100144552), dog RNF139 (609422), Domestic Rabbit RNF139 (100357210) ...More
UniProtKB ID:
Gene ID:
- Human(11236) Summary: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]
- Mouse(75841) ring finger protein 139
- Rat(315000) ring finger protein 139
- chicken(420338) ring finger protein 139
- sheep(101102651) ring finger protein 139
- naked mole-rat(101714326) ring finger protein 139
- domestic cat(101090488) ring finger protein 139
- Zebrafish(100144552) ring finger protein 139
- dog(609422) ring finger protein 139
- Domestic Rabbit(100357210) ring finger protein 139
- cow(788471) ring finger protein 139
- domestic guinea pig(100734055) ring finger protein 139
- Horse(100067392) ring finger protein 139
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