RGS4
regulator of G-protein signaling 4
Synonyms:
RGP4, SCZD9
Species:
Human RGS4 (5999), Mouse Rgs4 (19736), Rat Rgs4 (29480), domestic guinea pig Rgs4 (100717645), naked mole-rat Rgs4 (101713440), domestic cat RGS4 (101083058), chicken RGS4 (378901), sheep RGS4 (100381246), cow RGS4 (617437), dog RGS4 (488666) ...More
UniProtKB ID:
Gene ID:
- Human(5999) Summary: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19736) regulator of G-protein signaling 4
- Rat(29480) regulator of G-protein signaling 4
- domestic guinea pig(100717645) regulator of G-protein signaling 4
- naked mole-rat(101713440) regulator of G-protein signaling 4
- domestic cat(101083058) regulator of G-protein signaling 4
- chicken(378901) regulator of G-protein signaling 4
- sheep(100381246) regulator of G-protein signaling 4
- cow(617437) regulator of G-protein signaling 4
- dog(488666) regulator of G-protein signaling 4
- Zebrafish(569876) regulator of G-protein signalling 4
- Domestic Rabbit(100009014) regulator of G-protein signaling 4
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