RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
Synonyms:
C3G, GRF2
Species:
Human RAPGEF1 (2889), Mouse Rapgef1 (107746), Rat Rapgef1 (63881), naked mole-rat Rapgef1 (101714387), sheep RAPGEF1 (101121164), chicken RAPGEF1 (417173), domestic cat RAPGEF1 (101099507), Horse RAPGEF1 (100069527), cow RAPGEF1 (520454), domestic guinea pig Rapgef1 (100727953)
UniProtKB ID:
Gene ID:
- Human(2889) Summary: This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(107746) Rap guanine nucleotide exchange factor (GEF) 1
- Rat(63881) Rap guanine nucleotide exchange factor (GEF) 1
- naked mole-rat(101714387) Rap guanine nucleotide exchange factor (GEF) 1
- sheep(101121164) Rap guanine nucleotide exchange factor (GEF) 1
- chicken(417173) Rap guanine nucleotide exchange factor (GEF) 1
- domestic cat(101099507) Rap guanine nucleotide exchange factor (GEF) 1
- Horse(100069527) Rap guanine nucleotide exchange factor (GEF) 1
- cow(520454) Rap guanine nucleotide exchange factor (GEF) 1
- domestic guinea pig(100727953) Rap guanine nucleotide exchange factor (GEF) 1
- dog(491286) Rap guanine nucleotide exchange factor (GEF) 1
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