PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
Synonyms:
CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP
Species:
Human PSTPIP1 (9051), Mouse Pstpip1 (19200), Rat Pstpip1 (300732), sheep PSTPIP1 (101116939), Horse PSTPIP1 (100050881), domestic cat PSTPIP1 (101100213), dog PSTPIP1 (611757), chicken PSTPIP1 (415349), cow PSTPIP1 (513924), naked mole-rat Pstpip1 (101723975)
UniProtKB ID:
Gene ID:
- Human(9051) Summary: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq, Jul 2008]
- Mouse(19200) proline-serine-threonine phosphatase-interacting protein 1
- Rat(300732) proline-serine-threonine phosphatase-interacting protein 1
- sheep(101116939) proline-serine-threonine phosphatase interacting protein 1
- Horse(100050881) proline-serine-threonine phosphatase interacting protein 1
- domestic cat(101100213) proline-serine-threonine phosphatase interacting protein 1
- dog(611757) proline-serine-threonine phosphatase interacting protein 1
- chicken(415349) proline-serine-threonine phosphatase interacting protein 1
- cow(513924) proline-serine-threonine phosphatase interacting protein 1
- naked mole-rat(101723975) proline-serine-threonine phosphatase interacting protein 1
- domestic guinea pig(100732350) proline-serine-threonine phosphatase interacting protein 1
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