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Merck

PSMD5

proteasome (prosome, macropain) 26S subunit, non-ATPase, 5

Synonyms:
S5B
Species:
Human PSMD5 (5711), Mouse Psmd5 (66998), Rat Psmd5 (296651), dog PSMD5 (474703), domestic cat PSMD5 (101086760), Zebrafish psmd5 (550235), chicken PSMD5 (417125), naked mole-rat Psmd5 (101712371), domestic guinea pig Psmd5 (100723691), sheep PSMD5 (101122326) ...More
UniProtKB ID:
Q16401, B4DZM8, Q15045, Q4VXG8
Gene ID:
  • Human(5711) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly. [provided by RefSeq, Jul 2012]
  • Mouse(66998) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • Rat(296651) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • dog(474703) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • domestic cat(101086760) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • Zebrafish(550235) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • chicken(417125) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • naked mole-rat(101712371) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • domestic guinea pig(100723691) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • sheep(101122326) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • Domestic Rabbit(100339098) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • cow(515021) proteasome (prosome, macropain) 26S subunit, non-ATPase, 5

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