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Merck

PRODH

proline dehydrogenase (oxidase) 1

Synonyms:
HSPOX2, PIG6, POX, PRODH1, PRODH2, TP53I6
Species:
Human PRODH (5625), Mouse Prodh (19125), Rat Prodh (680409), Horse PRODH (100050480), domestic cat PRODH (101100421), cow PRODH (505094), domestic guinea pig Prodh (100732617), dog PRODH (477562), chicken PRODH (770734), naked mole-rat Prodh (101699174)
UniProtKB ID:
O43272, A6NF53, O14680, Q0P507, Q147W8, Q504W1, Q59FI8, Q6NV86
Gene ID:
  • Human(5625) Summary: This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
  • Mouse(19125) proline dehydrogenase
  • Rat(680409) proline dehydrogenase (oxidase) 1
  • Horse(100050480) proline dehydrogenase (oxidase) 1
  • domestic cat(101100421) proline dehydrogenase (oxidase) 1
  • cow(505094) proline dehydrogenase (oxidase) 1
  • domestic guinea pig(100732617) proline dehydrogenase (oxidase) 1
  • dog(477562) proline dehydrogenase (oxidase) 1
  • chicken(770734) proline dehydrogenase (oxidase) 1
  • naked mole-rat(101699174) proline dehydrogenase (oxidase) 1

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