PRKCH
protein kinase C, eta
Synonyms:
PKC-L, PKCL, PRKCL, nPKC-eta
Species:
Human PRKCH (5583), Mouse Prkch (18755), Rat Prkch (81749), Horse PRKCH (100051560), domestic guinea pig Prkch (100736222), domestic cat PRKCH (101082413), dog PRKCH (490722), Domestic Rabbit PRKCH (100344184), sheep PRKCH (101105574), cow PRKCH (518542) ...More
UniProtKB ID:
Gene ID:
- Human(5583) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq, Jul 2008]
- Mouse(18755) protein kinase C, eta
- Rat(81749) protein kinase C, eta
- Horse(100051560) protein kinase C, eta
- domestic guinea pig(100736222) protein kinase C, eta
- domestic cat(101082413) protein kinase C, eta
- dog(490722) protein kinase C, eta
- Domestic Rabbit(100344184) protein kinase C, eta
- sheep(101105574) protein kinase C, eta
- cow(518542) protein kinase C, eta
- chicken(423518) protein kinase C, eta
- naked mole-rat(101716769) protein kinase C, eta
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Small Molecule - Agonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-PKCη (Thr655) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Small Molecule - Inhibitor
Product Number
Description
Species