PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
Synonyms:
PKACA
Species:
Human PRKACA (5566), Mouse Prkaca (18747), Rat Prkaca (25636), naked mole-rat Prkaca (101707235), sheep PRKACA (443094), domestic guinea pig Prkaca (100735694), dog PRKACA (403556), Horse PRKACA (100064302), cow PRKACA (282322), domestic cat PRKACA (101090494)
UniProtKB ID:
Gene ID:
- Human(5566) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(18747) protein kinase, cAMP dependent, catalytic, alpha
- Rat(25636) protein kinase, cAMP-dependent, catalytic, alpha
- naked mole-rat(101707235) protein kinase, cAMP-dependent, catalytic, alpha
- sheep(443094) protein kinase, cAMP-dependent, catalytic, alpha
- domestic guinea pig(100735694) protein kinase, cAMP-dependent, catalytic, alpha
- dog(403556) protein kinase, cAMP-dependent, catalytic, alpha
- Horse(100064302) protein kinase, cAMP-dependent, catalytic, alpha
- cow(282322) protein kinase, cAMP-dependent, catalytic, alpha
- domestic cat(101090494) protein kinase, cAMP-dependent, catalytic, alpha
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Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PKA Protein, Recombinant, 10 µg, Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.,
Species