PRAME
preferentially expressed antigen in melanoma
Synonyms:
CT130, MAPE, OIP-4, OIP4
Species:
Human PRAME (23532), Mouse Prame (75829), Rat Prame (680000), naked mole-rat Prame (101711995), dog PRAME (477552), Horse PRAME (100061889), domestic cat PRAME (101086260), cow PRAME (528601), cow PRAME (785023), sheep PRAME (101108258)
UniProtKB ID:
Gene ID:
- Human(23532) Summary: This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
- Mouse(75829) preferentially expressed antigen in melanoma
- Rat(680000) preferentially expressed antigen in melanoma
- naked mole-rat(101711995) preferentially expressed antigen in melanoma
- dog(477552) preferentially expressed antigen in melanoma
- Horse(100061889) preferentially expressed antigen in melanoma
- domestic cat(101086260) preferentially expressed antigen in melanoma
- cow(528601) preferentially expressed antigen in melanoma
- cow(785023) preferentially expressed antigen in melanoma
- sheep(101108258) preferentially expressed antigen in melanoma
- domestic guinea pig(100731688) preferentially expressed antigen in melanoma
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