POU2F3
POU class 2 homeobox 3
Synonyms:
Epoc-1, OCT-11, OCT11, OTF-11, PLA-1, PLA1, Skn-1a
Species:
Human POU2F3 (25833), Mouse Pou2f3 (18988), Rat Pou2f3 (116544), cow POU2F3 (516493), dog POU2F3 (610476), chicken POU2F3 (428240), naked mole-rat Pou2f3 (101715283), domestic guinea pig Pou2f3 (100716380), sheep POU2F3 (101110172), Zebrafish pou2f3 (553427)
UniProtKB ID:
Gene ID:
- Human(25833) Summary: This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
- Mouse(18988) POU domain, class 2, transcription factor 3
- Rat(116544) POU class 2 homeobox 3
- cow(516493) POU class 2 homeobox 3
- dog(610476) POU class 2 homeobox 3
- chicken(428240) POU class 2 homeobox 3
- naked mole-rat(101715283) POU class 2 homeobox 3
- domestic guinea pig(100716380) POU class 2 homeobox 3
- sheep(101110172) POU class 2 homeobox 3
- Zebrafish(553427) POU class 2 homeobox 3
- domestic cat(101098740) POU class 2 homeobox 3
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