PLP1
proteolipid protein 1
Synonyms:
GPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2
Species:
Human PLP1 (5354), Mouse Plp1 (18823), Rat Plp1 (24943), Thale Cress PLP1 (829861), dog PLP1 (481002), naked mole-rat Plp1 (101699252), domestic guinea pig Plp1 (100714212), Domestic Rabbit PLP1 (100009169), sheep PLP1 (101121072), cow PLP1 (281410) ...More
UniProtKB ID:
Gene ID:
- Human(5354) Summary: This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18823) proteolipid protein (myelin) 1
- Rat(24943) proteolipid protein 1
- Thale Cress(829861) patatin-related phospholipase A
- dog(481002) proteolipid protein 1
- naked mole-rat(101699252) proteolipid protein 1
- domestic guinea pig(100714212) proteolipid protein 1
- Domestic Rabbit(100009169) proteolipid protein 1
- sheep(101121072) proteolipid protein 1
- cow(281410) proteolipid protein 1
- domestic cat(101098610) proteolipid protein 1
- chicken(396214) proteolipid protein 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Myelin Proteolipid Protein Antibody, CT, clone PLPC1, clone PLPC1, Chemicon®, from mouse,
Species Reactivity
mammals
Application
immunohistochemistry
western blot
western blot
Anti-Proteolipid Protein Antibody, Chemicon®, from chicken,
Species Reactivity
mouse
Application
immunocytochemistry
immunohistochemistry
immunohistochemistry