PFKL
phosphofructokinase, liver
Synonyms:
PFK-B
Species:
Human PFKL (5211), Mouse Pfkl (18641), Rat Pfkl (25741), dog PFKL (487797), chicken PFKL (769850), domestic guinea pig Pfkl (100720033), domestic cat PFKL (101090792), cow PFKL (508683), naked mole-rat Pfkl (101724978)
UniProtKB ID:
Gene ID:
- Human(5211) Summary: Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD). [provided by RefSeq, Aug 2008]
- Mouse(18641) phosphofructokinase, liver, B-type
- Rat(25741) phosphofructokinase, liver
- dog(487797) phosphofructokinase, liver
- chicken(769850) phosphofructokinase, liver
- domestic guinea pig(100720033) phosphofructokinase, liver
- domestic cat(101090792) phosphofructokinase, liver
- cow(508683) phosphofructokinase, liver
- naked mole-rat(101724978) phosphofructokinase, liver
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