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Merck

PEMT

phosphatidylethanolamine N-methyltransferase

Synonyms:
PEAMT, PEMPT, PEMT2, PNMT
Species:
UniProtKB ID:
Gene ID:
  • Human(10400) Summary: Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]
  • Mouse(18618) phosphatidylethanolamine N-methyltransferase
  • Rat(25511) phosphatidylethanolamine N-methyltransferase
  • Zebrafish(393127) phosphatidylethanolamine N-methyltransferase
  • chicken(416508) phosphatidylethanolamine N-methyltransferase
  • dog(479526) phosphatidylethanolamine N-methyltransferase
  • naked mole-rat(101706125) phosphatidylethanolamine N-methyltransferase
  • cow(360197) phosphatidylethanolamine N-methyltransferase
  • domestic guinea pig(100731090) phosphatidylethanolamine N-methyltransferase
  • domestic cat(101088035) phosphatidylethanolamine N-methyltransferase

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PEMT Antibody (CT), from rabbit,
Species Reactivity
human
Application
ELISA
immunocytochemistry

western blot