PDK1
pyruvate dehydrogenase kinase, isozyme 1
Synonyms:
Species:
Human PDK1 (5163), Mouse Pdk1 (228026), Rat Pdk1 (116551), fruit fly Pdk1 (38017), Zebrafish pdk1 (555840), Thale Cress PDK1 (830330), Horse PDK1 (100064091), domestic guinea pig Pdk1 (100715937), naked mole-rat Pdk1 (101705587), sheep PDK1 (101113205) ...More
UniProtKB ID:
Gene ID:
- Human(5163) Summary: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
- Mouse(228026) pyruvate dehydrogenase kinase, isoenzyme 1
- Rat(116551) pyruvate dehydrogenase kinase, isozyme 1
- fruit fly(38017) Phosphoinositide-dependent kinase 1
- Zebrafish(555840) pyruvate dehydrogenase kinase, isozyme 1
- Thale Cress(830330) 3'-phosphoinositide-dependent protein kinase 1
- Horse(100064091) pyruvate dehydrogenase kinase, isozyme 1
- domestic guinea pig(100715937) pyruvate dehydrogenase kinase, isozyme 1
- naked mole-rat(101705587) pyruvate dehydrogenase kinase, isozyme 1
- sheep(101113205) pyruvate dehydrogenase kinase, isozyme 1
- Domestic Rabbit(100351323) pyruvate dehydrogenase kinase, isozyme 1
- cow(528655) pyruvate dehydrogenase kinase, isozyme 1
- domestic cat(101092705) pyruvate dehydrogenase kinase, isozyme 1
- dog(476828) pyruvate dehydrogenase kinase, isozyme 1
- chicken(425972) pyruvate dehydrogenase kinase, isozyme 1
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