PDGFA
platelet-derived growth factor alpha polypeptide
PDGF-A, PDGF1
Human PDGFA (5154), Mouse Pdgfa (18590), Rat Pdgfa (25266), domestic cat PDGFA (101087287), naked mole-rat Pdgfa (101725739), chicken PDGFA (374196), dog PDGFA (491597), cow PDGFA (505908)
- Human(5154) Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18590) platelet derived growth factor, alpha
- Rat(25266) platelet-derived growth factor alpha polypeptide
- domestic cat(101087287) platelet-derived growth factor alpha polypeptide
- naked mole-rat(101725739) platelet-derived growth factor alpha polypeptide
- chicken(374196) platelet-derived growth factor alpha polypeptide
- dog(491597) platelet-derived growth factor alpha polypeptide
- cow(505908) platelet-derived growth factor alpha polypeptide
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Platelet Derived Growth Factor-AA Protein, Recombinant human, The Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle & connective tissue.,
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