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Merck

PDE4A

phosphodiesterase 4A, cAMP-specific

Synonyms:
DPDE2, PDE4, PDE46
Species:
UniProtKB ID:
Gene ID:
  • Human(5141) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(18577) phosphodiesterase 4A, cAMP specific
  • Rat(25638) phosphodiesterase 4A, cAMP-specific
  • sheep(101117505) phosphodiesterase 4A, cAMP-specific
  • Domestic Rabbit(100009247) phosphodiesterase 4A, cAMP-specific
  • Zebrafish(572061) phosphodiesterase 4A, cAMP-specific
  • domestic cat(751107) phosphodiesterase 4A, cAMP-specific
  • dog(100683695) phosphodiesterase 4A, cAMP-specific
  • chicken(769860) phosphodiesterase 4A, cAMP-specific
  • domestic guinea pig(100135594) phosphodiesterase 4A, cAMP-specific
  • cow(512222) phosphodiesterase 4A, cAMP-specific
  • naked mole-rat(101717168) phosphodiesterase 4A, cAMP-specific

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Small Molecule - Antagonist

Product Number
Description
Species
Theophylline, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Theophylline, United States Pharmacopeia (USP) Reference Standard,
Species
human
Theophylline, anhydrous, ≥99%, powder,
Species
mouse, human, rat

Small Molecule - Inhibitor

Product Number
Description
Species
Theophylline, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Theophylline, United States Pharmacopeia (USP) Reference Standard,
Species
human
Theophylline, anhydrous, ≥99%, powder,
Species
mouse, human, rat