PARK7
parkinson protein 7
DJ-1, DJ1
Human PARK7 (11315), Mouse Park7 (57320), Rat Park7 (117287), domestic guinea pig Park7 (100723185), cow PARK7 (511268), Zebrafish park7 (449674), domestic cat PARK7 (101092868), dog PARK7 (479595), sheep PARK7 (101119489), chicken PARK7 (395277)
- Human(11315) Summary: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(57320) Parkinson disease (autosomal recessive, early onset) 7
- Rat(117287) parkinson protein 7
- domestic guinea pig(100723185) parkinson protein 7
- cow(511268) parkinson protein 7
- Zebrafish(449674) parkinson disease (autosomal recessive, early onset) 7
- domestic cat(101092868) parkinson protein 7
- dog(479595) parkinson protein 7
- sheep(101119489) parkinson protein 7
- chicken(395277) Parkinson disease (autosomal recessive, early onset) 7
- naked mole-rat(101723322) parkinson protein 7
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