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Merck

PAM

peptidylglycine alpha-amidating monooxygenase

Synonyms:
PAL, PHM
Species:
UniProtKB ID:
Gene ID:
  • Human(5066) Summary: This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq, Jul 2008]
  • Mouse(18484) peptidylglycine alpha-amidating monooxygenase
  • Rat(25508) peptidylglycine alpha-amidating monooxygenase
  • Zebrafish(570822) peptidylglycine alpha-amidating monooxygenase
  • chicken(427274) peptidylglycine alpha-amidating monooxygenase
  • dog(479145) peptidylglycine alpha-amidating monooxygenase
  • domestic cat(101084598) peptidylglycine alpha-amidating monooxygenase
  • Horse(791244) peptidylglycine alpha-amidating monooxygenase
  • cow(280890) peptidylglycine alpha-amidating monooxygenase
  • sheep(101112815) peptidylglycine alpha-amidating monooxygenase
  • Domestic Rabbit(100352005) peptidylglycine alpha-amidating monooxygenase
  • domestic guinea pig(100713254) peptidylglycine alpha-amidating monooxygenase
  • naked mole-rat(101716909) peptidylglycine alpha-amidating monooxygenase

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