NUDT2
nudix (nucleoside diphosphate linked moiety X)-type motif 2
Synonyms:
APAH1
Species:
Human NUDT2 (318), Mouse Nudt2 (66401), Rat Nudt2 (297998), Zebrafish nudt2 (436595), chicken NUDT2 (427399), domestic cat NUDT2 (101082099), cow NUDT2 (768044), dog NUDT2 (474746), Thale Cress NUDT2 (834816), domestic guinea pig Nudt2 (100721527) ...More
UniProtKB ID:
Gene ID:
- Human(318) Summary: This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]
- Mouse(66401) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- Rat(297998) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- Zebrafish(436595) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- chicken(427399) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- domestic cat(101082099) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- cow(768044) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- dog(474746) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- Thale Cress(834816) nudix hydrolase 2
- domestic guinea pig(100721527) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- naked mole-rat(101699878) nudix (nucleoside diphosphate linked moiety X)-type motif 2
- sheep(101123091) nudix (nucleoside diphosphate linked moiety X)-type motif 2
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