NDRG1
N-myc downstream regulated 1
Synonyms:
CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5
Species:
Human NDRG1 (10397), Mouse Ndrg1 (17988), Rat Ndrg1 (299923), cow NDRG1 (504499), naked mole-rat Ndrg1 (101722001), domestic guinea pig Ndrg1 (100728790), sheep NDRG1 (101120172), domestic cat NDRG1 (101089078), Horse NDRG1 (100068997), dog NDRG1 (482049)
UniProtKB ID:
Gene ID:
- Human(10397) Summary: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- Mouse(17988) N-myc downstream regulated gene 1
- Rat(299923) N-myc downstream regulated 1
- cow(504499) N-myc downstream regulated 1
- naked mole-rat(101722001) N-myc downstream regulated 1
- domestic guinea pig(100728790) N-myc downstream regulated 1
- sheep(101120172) N-myc downstream regulated 1
- domestic cat(101089078) N-myc downstream regulated 1
- Horse(100068997) N-myc downstream regulated 1
- dog(482049) N-myc downstream regulated 1
- chicken(420321) N-myc downstream regulated 1
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