MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
Synonyms:
Species:
Human MTHFR (4524), Mouse Mthfr (17769), Rat Mthfr (362657), chicken MTHFR (419489), Zebrafish mthfr (567547), naked mole-rat Mthfr (101719335), domestic guinea pig Mthfr (100715703), Domestic Rabbit MTHFR (100352874), sheep MTHFR (101111645), cow MTHFR (497032) ...More
UniProtKB ID:
Gene ID:
- Human(4524) Summary: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]
- Mouse(17769) 5,10-methylenetetrahydrofolate reductase
- Rat(362657) methylenetetrahydrofolate reductase (NAD(P)H)
- chicken(419489) methylenetetrahydrofolate reductase (NAD(P)H)
- Zebrafish(567547) methylenetetrahydrofolate reductase (NAD(P)H)
- naked mole-rat(101719335) methylenetetrahydrofolate reductase (NAD(P)H)
- domestic guinea pig(100715703) methylenetetrahydrofolate reductase (NAD(P)H)
- Domestic Rabbit(100352874) methylenetetrahydrofolate reductase (NAD(P)H)
- sheep(101111645) methylenetetrahydrofolate reductase (NAD(P)H)
- cow(497032) methylenetetrahydrofolate reductase (NAD(P)H)
- dog(478230) methylenetetrahydrofolate reductase (NAD(P)H)
- Horse(100050979) methylenetetrahydrofolate reductase (NAD(P)H)
- domestic cat(101100576) methylenetetrahydrofolate reductase (NAD(P)H)
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