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Merck

MRPS17

mitochondrial ribosomal protein S17

Synonyms:
HSPC011, MRP-S17, RPMS17, S17mt
Species:
Human MRPS17 (51373), Mouse Mrps17 (66258), Rat Mrps17 (288621), dog MRPS17 (100688077), domestic cat MRPS17 (101082711), sheep MRPS17 (101108014), cow MRPS17 (508143), naked mole-rat Mrps17 (101697932), domestic guinea pig Mrps17 (100719305), fruit fly mRpS17 (37872)
UniProtKB ID:
Q9Y2R5, Q86X15
Gene ID:
  • Human(51373) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008]
  • Mouse(66258) mitochondrial ribosomal protein S17
  • Rat(288621) mitochondrial ribosomal protein S17
  • dog(100688077) mitochondrial ribosomal protein S17
  • domestic cat(101082711) mitochondrial ribosomal protein S17
  • sheep(101108014) mitochondrial ribosomal protein S17
  • cow(508143) mitochondrial ribosomal protein S17
  • naked mole-rat(101697932) mitochondrial ribosomal protein S17
  • domestic guinea pig(100719305) mitochondrial ribosomal protein S17
  • fruit fly(37872) mitochondrial ribosomal protein S17
  • chicken(417538) mitochondrial ribosomal protein S17

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