MAPK14
mitogen-activated protein kinase 14
Synonyms:
CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
Species:
Human MAPK14 (1432), Mouse Mapk14 (26416), Rat Mapk14 (81649), naked mole-rat Mapk14 (101715692), domestic guinea pig Mapk14 (100723285), chicken MAPK14 (421183), Horse MAPK14 (100063532), dog MAPK14 (403856), domestic cat MAPK14 (101101135), Domestic Rabbit MAPK14 (100341695) ...More
UniProtKB ID:
Gene ID:
- Human(1432) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(26416) mitogen-activated protein kinase 14
- Rat(81649) mitogen activated protein kinase 14
- naked mole-rat(101715692) mitogen-activated protein kinase 14
- domestic guinea pig(100723285) mitogen-activated protein kinase 14
- chicken(421183) mitogen-activated protein kinase 14
- Horse(100063532) mitogen-activated protein kinase 14
- dog(403856) mitogen-activated protein kinase 14
- domestic cat(101101135) mitogen-activated protein kinase 14
- Domestic Rabbit(100341695) mitogen-activated protein kinase 14
- sheep(100217411) mitogen-activated protein kinase 14
- cow(534492) mitogen-activated protein kinase 14
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ELISA
Product Number
Description
Species
Cell-Based ELISA for detecting phospho-P38 MAPK (pThr180 / pTyr182) in cultured cell lines, 96 assays,
Species
human
Phospho-p38 α (pThr180 / pTyr182) ELISA Kit, fore detection of phospho-p38 alpha (pThr180 / pTyr182) in human or mouse cell and tissue lysates,
Species
human
Phospho-p38 α (pThr180 / pTyr182) and pan-p38 ELISA Kit, for detection of phospho-p38 alpha (pThr180 / pTyr182) and pan-p38 in human or mouse cell and tissue lysates,
Species
human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Species
rat, human, mouse
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MAPK14, (C-terminal) antibody produced in mouse, clone 3D5, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-phospho-p38 (Thr180/Tyr182) Antibody, clone 6E5.2, clone 6E5.2, from mouse,
Species Reactivity
human, mouse
Application
immunocytochemistry
western blot
western blot
Anti-phospho-p38α(Thr180/Tyr182) Antibody, clone 8.78.8, rabbit monoclonal, culture supernatant, clone 8.78.8, from rabbit,
Species Reactivity
human, mouse, vertebrates
Application
immunofluorescence
western blot
western blot
Anti-phospho-p38α (Thr180/Tyr182) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot