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Merck

MAP4K5

mitogen-activated protein kinase kinase kinase kinase 5

Synonyms:
GCKR, KHS, KHS1, MAPKKKK5
Species:
Human MAP4K5 (11183), Mouse Map4k5 (399510), Rat Map4k5 (503027), naked mole-rat Map4k5 (101697393), cow MAP4K5 (781335), domestic guinea pig Map4k5 (100727959), chicken MAP4K5 (423576), sheep MAP4K5 (101103818), Domestic Rabbit MAP4K5 (100346909), Horse MAP4K5 (100066454) ...More
UniProtKB ID:
Q9Y4K4, Q8IYF6
Gene ID:
  • Human(11183) Summary: This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(399510) mitogen-activated protein kinase kinase kinase kinase 5
  • Rat(503027) mitogen-activated protein kinase kinase kinase kinase 5
  • naked mole-rat(101697393) mitogen-activated protein kinase kinase kinase kinase 5
  • cow(781335) mitogen-activated protein kinase kinase kinase kinase 5
  • domestic guinea pig(100727959) mitogen-activated protein kinase kinase kinase kinase 5
  • chicken(423576) mitogen-activated protein kinase kinase kinase kinase 5
  • sheep(101103818) mitogen-activated protein kinase kinase kinase kinase 5
  • Domestic Rabbit(100346909) mitogen-activated protein kinase kinase kinase kinase 5
  • Horse(100066454) mitogen-activated protein kinase kinase kinase kinase 5
  • dog(490685) mitogen-activated protein kinase kinase kinase kinase 5
  • domestic cat(101095501) mitogen-activated protein kinase kinase kinase kinase 5
  • Zebrafish(334565) mitogen-activated protein kinase kinase kinase kinase 5

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