MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
Synonyms:
CCA4, c-MAF
Species:
Human MAF (4094), Mouse Maf (17132), Rat Maf (54267), Zebrafish maf (114467), chicken MAF (693248), cow MAF (782481), domestic guinea pig Maf (100725532), naked mole-rat Maf (101698937)
UniProtKB ID:
Gene ID:
- Human(4094) Summary: The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
- Mouse(17132) avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
- Rat(54267) v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
- Zebrafish(114467) v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog
- chicken(693248) v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
- cow(782481) v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
- domestic guinea pig(100725532) v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
- naked mole-rat(101698937) v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
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