MACC1
metastasis associated in colon cancer 1
Synonyms:
7A5, SH3BP4L
Species:
Human MACC1 (346389), Mouse Macc1 (238455), Rat Macc1 (314539), domestic cat MACC1 (101087465), dog MACC1 (482343), chicken MACC1 (420604), Zebrafish macc1 (558777), naked mole-rat Macc1 (101703897), domestic guinea pig Macc1 (100731012), Domestic Rabbit MACC1 (100358685) ...More
UniProtKB ID:
Gene ID:
- Human(346389) Summary: MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]
- Mouse(238455) metastasis associated in colon cancer 1
- Rat(314539) metastasis associated in colon cancer 1
- domestic cat(101087465) metastasis associated in colon cancer 1
- dog(482343) metastasis associated in colon cancer 1
- chicken(420604) metastasis associated in colon cancer 1
- Zebrafish(558777) metastasis associated in colon cancer 1
- naked mole-rat(101703897) metastasis associated in colon cancer 1
- domestic guinea pig(100731012) metastasis associated in colon cancer 1
- Domestic Rabbit(100358685) metastasis associated in colon cancer 1
- cow(521867) metastasis associated in colon cancer 1
- sheep(101107275) metastasis associated in colon cancer 1
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