LRP1
low density lipoprotein receptor-related protein 1
Synonyms:
A2MR, APOER, APR, CD91, IGFBP3R, LRP, LRP1A, TGFBR5
Species:
Human LRP1 (4035), Mouse Lrp1 (16971), Rat Lrp1 (299858), dog LRP1 (481124), cow LRP1 (533894), sheep LRP1 (101120656), chicken LRP1 (396170), domestic guinea pig Lrp1 (100726418), Domestic Rabbit LRP1 (100009571), Thale Cress LRP1 (831108) ...More
UniProtKB ID:
Gene ID:
- Human(4035) Summary: The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq, Jan 2010]
- Mouse(16971) low density lipoprotein receptor-related protein 1
- Rat(299858) low density lipoprotein receptor-related protein 1
- dog(481124) low density lipoprotein receptor-related protein 1
- cow(533894) low density lipoprotein receptor-related protein 1
- sheep(101120656) low density lipoprotein receptor-related protein 1
- chicken(396170) low density lipoprotein receptor-related protein 1
- domestic guinea pig(100726418) low density lipoprotein receptor-related protein 1
- Domestic Rabbit(100009571) low density lipoprotein receptor-related protein 1
- Thale Cress(831108) lateral root primordium protein-like protein
- fruit fly(35799) LDL receptor protein 1
- naked mole-rat(101723541) low density lipoprotein receptor-related protein 1
- domestic cat(101090780) low density lipoprotein receptor-related protein 1
- Domestic Rabbit(100009547) low density lipoprotein receptor-related protein 1
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