LOXL1
lysyl oxidase-like 1
Synonyms:
LOL, LOXL
Species:
Human LOXL1 (4016), Mouse Loxl1 (16949), Rat Loxl1 (315714), dog LOXL1 (100686150), domestic guinea pig Loxl1 (100720568), domestic cat LOXL1 (101089616), naked mole-rat Loxl1 (101710365), chicken LOXL1 (426411), sheep LOXL1 (101112424), Zebrafish loxl1 (560115) ...More
UniProtKB ID:
Gene ID:
- Human(4016) Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
- Mouse(16949) lysyl oxidase-like 1
- Rat(315714) lysyl oxidase-like 1
- dog(100686150) lysyl oxidase-like 1
- domestic guinea pig(100720568) lysyl oxidase-like 1
- domestic cat(101089616) lysyl oxidase-like 1
- naked mole-rat(101710365) lysyl oxidase-like 1
- chicken(426411) lysyl oxidase-like 1
- sheep(101112424) lysyl oxidase-like 1
- Zebrafish(560115) lysyl oxidase-like 1
- cow(281903) lysyl oxidase-like 1
- Horse(100051862) lysyl oxidase-like 1
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