LBP
lipopolysaccharide binding protein
Synonyms:
BPIFD2
Species:
Human LBP (3929), Mouse Lbp (16803), Rat Lbp (29469), Horse LBP (100070103), domestic cat LBP (101097963), dog LBP (485869), naked mole-rat Lbp (101697726), domestic guinea pig Lbp (100731373), Domestic Rabbit LBP (100009124), sheep LBP (101104595)
UniProtKB ID:
Gene ID:
- Human(3929) Summary: The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]
- Mouse(16803) lipopolysaccharide binding protein
- Rat(29469) lipopolysaccharide binding protein
- Horse(100070103) lipopolysaccharide binding protein
- domestic cat(101097963) lipopolysaccharide binding protein
- dog(485869) lipopolysaccharide binding protein
- naked mole-rat(101697726) lipopolysaccharide binding protein
- domestic guinea pig(100731373) lipopolysaccharide binding protein
- Domestic Rabbit(100009124) lipopolysaccharide binding protein
- sheep(101104595) lipopolysaccharide binding protein
- cow(512242) lipopolysaccharide binding protein
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