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Merck

KLRB1

killer cell lectin-like receptor subfamily B, member 1

Synonyms:
CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
Species:
Human KLRB1 (3820), Mouse Klrb1 (100043861), Rat Klrb1 (689817), cow KLRB1 (407181), domestic cat KLRB1 (101081737), dog KLRB1 (100684789)
UniProtKB ID:
Q12918, Q24K24
Gene ID:
  • Human(3820) Summary: Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
  • Mouse(100043861) killer cell lectin-like receptor subfamily B member 1
  • Rat(689817) killer cell lectin-like receptor subfamily B, member 1
  • cow(407181) killer cell lectin-like receptor subfamily B, member 1
  • domestic cat(101081737) killer cell lectin-like receptor subfamily B, member 1
  • dog(100684789) killer cell lectin-like receptor subfamily B, member 1

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