KEAP1
kelch-like ECH-associated protein 1
Synonyms:
INrf2, KLHL19
Species:
Human KEAP1 (9817), Mouse Keap1 (50868), Rat Keap1 (117519), fruit fly Keap1 (42062), cow KEAP1 (532791), domestic cat KEAP1 (101091260), dog KEAP1 (476713), domestic guinea pig Keap1 (100713871), naked mole-rat Keap1 (101718777), sheep KEAP1 (101113845)
UniProtKB ID:
Gene ID:
- Human(9817) Summary: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(50868) kelch-like ECH-associated protein 1
- Rat(117519) Kelch-like ECH-associated protein 1
- fruit fly(42062) CG3962 gene product from transcript CG3962-RC
- cow(532791) kelch-like ECH-associated protein 1
- domestic cat(101091260) kelch-like ECH-associated protein 1
- dog(476713) kelch-like ECH-associated protein 1
- domestic guinea pig(100713871) kelch-like ECH-associated protein 1
- naked mole-rat(101718777) kelch-like ECH-associated protein 1
- sheep(101113845) kelch-like ECH-associated protein 1
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