KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
Synonyms:
KIR1.1, ROMK, ROMK1
Species:
Human KCNJ1 (3758), Mouse Kcnj1 (56379), Rat Kcnj1 (24521), chicken KCNJ1 (428236), Horse KCNJ1 (100072580), domestic cat KCNJ1 (101091140), cow KCNJ1 (539250), dog KCNJ1 (489285), naked mole-rat Kcnj1 (101720253), domestic guinea pig Kcnj1 (100722828)
UniProtKB ID:
Gene ID:
- Human(3758) Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(56379) potassium inwardly-rectifying channel, subfamily J, member 1
- Rat(24521) potassium inwardly-rectifying channel, subfamily J, member 1
- chicken(428236) potassium inwardly-rectifying channel, subfamily J, member 1
- Horse(100072580) potassium inwardly-rectifying channel, subfamily J, member 1
- domestic cat(101091140) potassium inwardly-rectifying channel, subfamily J, member 1
- cow(539250) potassium inwardly-rectifying channel, subfamily J, member 1
- dog(489285) potassium inwardly-rectifying channel, subfamily J, member 1
- naked mole-rat(101720253) potassium inwardly-rectifying channel, subfamily J, member 1
- domestic guinea pig(100722828) potassium inwardly-rectifying channel, subfamily J, member 1
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